Monday, 1st September Australasian RNA Biology and Biotechnology Association 2025 Conference

From Stem Cells to Wiring Human Neural Circuits in Living Systems to Discover Therapeutics

Prof Sergiu Pasca - Stanford University

(40 mins & 5 mins Q&A)

• Unlocking the hidden world of RNA isoforms in brain development and neuropsychiatric disorders - Michael B Clark
• Spatial and functional characterisation of brain lncRNAs highlights their importance in cognition - Saba Altaf
• CRISPRi Screening in Cultured Human Astrocytes Uncovers Distal Enhancers Controlling Genes Dysregulated in Alzheimer's Disease - Nicole Green

Panellists:

Dr Natalia Sampaio - Team Leader - Hudson Institute Melbourne 
A/Prof. Glen Reid - Laboratory head - University of Otago
A/Prof. Martin Smith - Director - Ramaciotti Centre for Genomics

• RegLLM: A RNA Foundation Large Language Model for Decoding the Post-Transcriptional Regulatory Code - Jiayu Wen
• Interpretable machine learning for the systematic annotation of functional domains in long non-coding RNAs  - Martin A Smith
• Nanopore long-read sequencing CLIP uncovers isoform-specific RNA-protein interactions and unexpected RNA binding protein activities - Katrina Woodward
• Bioactive Metal-Organic Nanoparticles: A Versatile Platform for RNA Delivery - Jingqu Chen

• RNA for agriculture – Expanding the frontiers of sustainable crop protection - Neena Mitter
• Synthetic RNA-binding proteins for controlling gene expression - Ian Small
• Small RNA biogenesis: co-transcriptional regulation and RNA modifications - Jakub Dolata
• Protecting crops from lepidopteran insect pests using RNAi - Soumitra Patekar

• Investigating Transcript Diversity as a Driver of Melanoma Progression and Metastasis Using Nanopore Long-Read RNA Sequencing - Jun Yao Teow
• Reactivating tumour suppressors in cancer with mRNA therapeutics. - Eunice Gee
• Development of mRNA vaccines for Hepatitis C virus - Joey McGregor
• Developing small RNAs as inhibitors of oncogenic signalling pathways - Saba Ataei Kachooei
• Regulation of long non-coding (lncRNAs) in epithelial-mesenchymal transition - Chi Yau Liu
• TERRA RNA in cancer and aging - Hsueh-Ping Chu
• 3-bit fluorescence reporting using RNA aptamers - Bradley I. Harding
• Putting the AS in MASLD: Investigating the role of alternative splicing in liver disease - Natasha D Suriani
• Targeting Long Non-Coding RNA for Therapeutic Modulation of Brain Function  - Sonia Hesam-Shariati
• Self-Assembled Chiral Lipid Phases for Passive RNA Capture and Release - Dev C Chauhan
• Investigating the role of mRNA transcript diversity in therapy-induced plasticity and resistance in melanoma - Lorey Smith
• The RNA Helicase Rig-I in Biomolecular Condensates - Xinyu (Yola) Li
• Integrated Design-to-Delivery Platform for Accelerating mRNA Vaccines and Therapeutics - Amatulla Nashikwala
• Multi-Omic RNA Architecture Reveals Coordinated Modification-Translation-Decay Networks During Nutrient Stress - Shafi Mahmud
• ZMYND8: A novel transcriptional regulator of the dorsal-ventral patterning of the brain - Juli Wang
• Investigating new mRNA-based immunotherapies for the management of Diffuse Midline Gliomas. - Ernest Moles
• FracFixR: A Compositional Framework for Accurate Cross-Fraction Transcript Quantification in RNA-seq - Alice Cleynen
• VIRMA amplification drives oncogenesis and chemoresistance in high-grade serous ovarian cancer - Jessica Tieng
• Development of a zebrafish platform to investigate cryptic exons in motor neurons in vivo - Sharlynn Wu
• A Conserved Nuclear Antisense Long Noncoding RNA Regulates Cell and Organ Size in Arabidopsis thaliana - Xingyu Wu
• MicroR159 controls a broad-spectrum pathogen defence mechanism in plants. - Anthony Millar
• Not so normal? RNA dysregulation in brain regions without hallmark neurodegenerative pathology - Natalie Grima
• Childhood Dementia Theratyping: Evaluating Variant Suitability For Antisense Oligonucleotide Therapy Development - Sujit S Krishnan
• Sequence-dependent modulation of viral-driven inflammation by a non-targeting 2’-O-Me gapmer oligonucleotide. - Sunil Sapkota
• Decoding RNA modification co-occurrence at single-molecule resolution - Stefan Prodic
• MULTIPLEXED ARTIFICIAL MICRORNA PROMOTE HIV LATENCY AND CAN PROVIDE FOR A FUNCTIONAL CURE OF HIV-1 - Rose Kitawi
• Multifunctional SRP68/72: From RNA Binding to Translational Control and Beyond - Sandro F Ataide
• Alternative splicing mediates androgen deprivation therapy resistance and metastasis in prostate cancer - Philip A Gregory
• Optimising the mRNA vaccine platform for enhanced efficacy against M. tuberculosis - Hannah Lukeman
• Mind the gap: Developing a bioinformatics pipeline to evaluate evolutionary conservation of lncRNAs secondary structures in Brassicaceae  - Gabriela Santos-Rodriguez
• Decoding Regulatory Outcomes of Bacterial sRNA–mRNA Interactions Using Machine Learning - Fatemeh Safari
• The NZ RNA Platform: A Flexible and Iterative Framework for RNA Therapeutics   - Jordan J Minnell
• Identifying Molecular Drivers of Neuroblastoma - Sepideh Mehrpour Layeghi
• Antisense oligonucleotide mediated reduction of C9ORF72 expansion containing transcripts in iPSC-derived motor neurons  - Leon Larcher
• Probing RNA Base Pairing and Ligand Interactions In Solution with Infrared-based Microfluidic Modulation Spectroscopy - Peter Davis
• Novel siRNA therapeutics targeting Human T-cell Leukaemia Virus Type-1 (HTLV-1) infection - Tiana Wang