Wednesday, 3rd September Australasian RNA Biology and Biotechnology Association 2025 Conference

• Decoding the (epi)transcriptome at single-molecule resolution - Eduardo Eyras
• Investigating the shape of polyadenylation across the mRNA lifecycle - Traude Beilharz
• tRNA modifications tune m⁶A-dependent mRNA decay - Sebastian A Leidel
• Human RNA Polymerase II is maintained in excess for robust transcriptional homeostasis - Alexander Gillis

• A cell-cycle mediated checkpoint that regulates mRNA export in response to replication stress - Vihandha Wickramasinghe
• RNA at the Immune interface - Cecile King
• Let’s get speckly! Examining paraspeckle formation in hypo-osmotic stress - Dane Webster

Moderator: Sarah Herridge, Director of Research and Scientific Affairs at BioNTech Australia

Panellists:

Nils Walter, Center for RNA Biomedicine, U. of Michigan, USA

Noelia Nebot, Conexias Advisory, Australia

Sue Fletcher, Murdoch University, Australia

• Novel Ionizable Lipids for LNPs with Improved Performance - Gavin Painter
• Development of Intranasal Antiviral RNA Therapeutics targeting SARS-CoV-2 (DARTS) - Chantelle L Ahlenstiel
• Whole-Cell Lipid Nanoparticles (WC-LNPs): A Modular RNA Delivery Platform with Tunable Tropism and Application Flexibility - Wenhuang Ban
• The HERACLES Trial: Novel 3-base Oligonucleotide Therapeutic Antagonises TLR7/8 in Autoimmune Skin Disease - Mary Speir

Prof Matt Disney - The Scripps Research Institute

(50 mins & 10 mins Q&A)

• Sequence-based design of small molecules targeting RNA structure - Matt D. Disney